Key Info

Basic Information

Prof. Dr. Gernot Marx
Faculty / Institution:
Project duration:
01.01.2016 to 31.12.2018
EU contribution:
374.200 euros


Mobile Autonomy for Children in End-stage Heart failure Therapy


The main goal of EIT MACH is CE certification and market entry of the new EXCOR® Active driving unit. Market entry is due soon, and it is expected to revolutionise how we perceive mechanical circulatory support therapy in the paediatric population. While the first year of the project created the necessary structures and networks, the second year of the project was mainly devoted to testing and education.

Testing has picked up speed. In a parallel setting of both human and animal blood testing, the effects of the alternative pressure curve induced by the new driver unit were analysed with regard to haemocompatibility, to shear stress and to activation of the coagulation cascade.

The educational work involved initiation of a platform for health care professionals and private persons to be trained on paediatric mechanical circulatory support. One of the main outputs of the final year of the EIT MACH action will be the release of the educational platform, which offers training for health care professionals, patients, their families and carSuccess Storyegivers.

Success story

The project "Mobile Autonomy for Children in End-Stage Heart Failure" (MACH) has won the 2020 Horizon Impact Award. This award is to recognize and celebrate outstanding EU-funded projects that have applied their results in projects that provide particular value for society. For further information, please see this short video or the RWTH press release


  • Newcastle University, United Kingdom
  Logo EIT Health

This activity has received funding from the European Institute of Innovation and Technology (EIT), a body of the European Union, under the Horizon 2020, the EU Framework Programme for Research and Innovation.